Comparison
Two Russian nasal peptides, one aimed at focus and one at calm. Below, each one is shown with its status, the state of the human evidence and what named experts have said, word for word.
iNot medical advice. We don’t recommend any peptide or dose, and this page does not say which one is “better”. Every dose below is a quote from the person named.
| Semax | Selank | |
|---|---|---|
| What it is | Discussed for focus and memory; registered as a medicine in Russia. | Discussed for calm and anxiety; registered as a medicine in Russia. |
| Category | Calm, focus & sleep | Calm, focus & sleep |
| Status | Registered in Russia; not approved (EU/UK/US) | Registered in Russia; not approved (EU/UK/US) |
| How well studied in people | Small human studies | Small human studies |
| Experts quoted | 6 | 5 |
| Dose statements | 8 | 5 |
Statements filed under one of them that also mention the other.
“And then there's Selank, which I always run with Semax. […] Same dosing as Selank and Semax, so they're 300 to 400 micrograms, maybe 600 if you're going crazy.”
Context: The cut removes his description of what Selank does. He says “Same dosing as Selank and Semax” while talking about Selank; we read it as “same dosing as Semax”.
One statement per expert (the earliest), out of 8 statements on the full page. Quotes are word for word, with cuts marked […].
“• Suggested dosing • 750 mcg per nasal spray in each nostril once a day. (total dose of 1500 mcg) • The stroke studies used up 18 mg a day”
Context: On the same slide he notes that Semax has poor oral delivery and can be given under the skin or into the nose. From his conference slides for doctors (Age Management Medicine Group); the slides are undated.
“to be clear, i've been using a thousand micrograms c-max upon waking inter-nasally like once per day so i administer 500 micrograms in each nostril with the nasal spray upon waking”
Context: “c-max” is how the captions render Semax. He was 10 days in and planned “four weeks and then take a break”.
“Semax: 1–2 sprays nasally.”
Context: Listed in his “Sample Stack for Brain Health”, which he introduces with “I recommend the following peptide stacks for various purposes”. The spray strength is not stated.
“Now, both are in nasal spray because we do want this in the brain. Nasal is optimal here. Doing can be anywhere around 1 milligram per application up to three times per day. Switching between nostrils. Some patients use it daily for cognitive demands. Others use it situationally like a bit of a neutropic where only when I need it. If you are running it every day, give yourself a break probably after 2 to 3 months.”
Context: “both” means Semax and Selank, which he presents as a pair (the captions render them “CAX” and “Seal”). He does not give separate amounts for each. “Doing” is how the captions render “Dosing”.
“Now, the Russian stuff comes as nasal drops with two strengths. We have a 0.1% solution for the cognitive boost and stroke recovery indications, and then a stronger 1% reserve for acute stroke in the hospital. One drop of the 0.1% is about 50 micrograms, and the labeled daily range runs from a few hundred up to a couple thousand micrograms. Usually only run for a couple days at a time. The gray market, meanwhile, is its own animal. Biohackers have reported using nasal sprays, usually somewhere between 100 and 1,000 micrograms a day, usually 5 days on, 2 days off.”
Context: He describes the Russian product label and what biohackers report, not his own use. He adds that injecting it under the skin has “no obvious upside” in his view.
“Typical dosing, 300 400 I mean, 600 micrograms is a lot. I don't typically go that high unless it's like I got to hammer it. Split into two doses, morning afternoon. You can cycle this a couple times a year. I don't recommend running as needed, but people do. […] I like structuring it to 21 to 30 days on and then off”
Context: Part of an epitalon-based stack. The cut removes “You're going to do what you want.”
One statement per expert (the earliest), out of 5 statements on the full page. Quotes are word for word, with cuts marked […].
“• Suggested dosing […] • 75 μg of Selank per nasal spray. The recommended dosage is 1-2 sprays per dose with 2- 3 doses per day (a max total of 675 μg/day)”
Context: The cut bullets say Selank has poor oral delivery and can be given under the skin or into the nose. From his conference slides for doctors (Age Management Medicine Group); the slides are undated.
“I've been doing this comparison with dosages of exactly a th000 micrograms SX nasal drops or subcutaneous administrations or 1,000 micrograms sank nasal drops or subc subcutaneous Administration so the dosing protocol has been exactly the same”
Context: “sank” is how the captions render Selank and “SX” Semax. In part 1 he says he used both for four weeks and then stopped.
“Selank: 1–2 sprays nasally.”
Context: Listed in his “Sample Stack for Brain Health”. The spray strength is not stated.
“Now, both are in nasal spray because we do want this in the brain. Nasal is optimal here. Doing can be anywhere around 1 milligram per application up to three times per day. Switching between nostrils. Some patients use it daily for cognitive demands. Others use it situationally like a bit of a neutropic where only when I need it. If you are running it every day, give yourself a break probably after 2 to 3 months.”
Context: “both” means Semax and Selank, which he presents as a pair (the captions render them “CAX” and “Seal”). He does not give separate amounts for each. “Doing” is how the captions render “Dosing”.
“And then there's Selank, which I always run with Semax. […] Same dosing as Selank and Semax, so they're 300 to 400 micrograms, maybe 600 if you're going crazy.”
Context: The cut removes his description of what Selank does. He says “Same dosing as Selank and Semax” while talking about Selank; we read it as “same dosing as Semax”.
The clinical study we could verify is in stroke rehabilitation, published in Russian. It is not a guide to nootropic use.
See the studies on the Semax page
The clinical studies we could verify were published in Russian and compared Selank with an older anti-anxiety drug. They are not a guide to dosing.
Compiled from the quotes and research already on each peptide page. Last updated 11 Oct 2026. More comparisons · Glossary