Expert profile
Physician; host of the Peptides and Longevity podcast (Big Doc Energy)
Holtorf is a US physician who hosts a podcast on peptides and longevity. Quotes here come from his solo introduction to peptide classes.
iNo endorsement. Dr Kent Holtorf is quoted for public statements only and does not endorse this site. Quotes are word for word; follow each link for the full context.
“and then aod is a fraction of growth hormone. It does not increase, um, igf1, which is how, uh, most the effects of growth hormone [… happen], but it has its own rejuvenating effects and also does boost metabolism”
Context: From his solo introduction to peptide classes on his podcast. He gives no dose.
“there's melanotan one and then two which is uh which is available: you get tan, you lose weight, increase libido, increase erectile function […] but the problem is if you're young that's great, you get tan, but if you're older it will bring out dark spots”
Context: From his solo introduction to peptide classes. The cut removes his nickname for it. He gives no dose.
“uh one probably the best anti-aging hormone, uh, studies show when you take it, uh, they've done studies, uh, basically people over 65 years old, uh, significant cardiovascular disease, spa for, for 14 years, uh, dramatic reduction immortality, morbidity, they live longer”
Context: Talking about the pineal peptides (epitalon and related). Auto-captions are garbled (“immortality” is probably “in mortality”); he does not name the study. The Khavinson studies we could verify are listed below.
“ss31, um, is in tons of Trials. It improves mitochondrial function. It's basically an antioxidant inside the mitochondria, uh, for right now it's very expensive to get the dose that works, but a lot of great studies coming out on that”
Context: He does not state the dose he means.
“Delta Sleep does, uh, like what it says, is a Sleep Center, but it's very anti-inflammatory, so one of the things it, it likely does is lower the inflammation in the hypothalamus and that really helps you get deep sleep”
Context: No dose given. Earlier he describes combining epitalon or other pineal peptides with delta sleep-inducing peptide for people who “can't sleep like myself”.
“thymus in alpha 1 is, uh, proof for infections, it raises that th1, uh, thymus”
Context: Captions are garbled: “thymus in alpha 1” is thymosin alpha-1 and “proof” is probably “approved”. It is approved in some countries outside the EU and US (see the notice above).
“antimicrobial peptides, um, ll37 is a big one, very broad range of antimicrobial, um, properties that your body secretes, actually stem cells secrete them, it also stimulates stem cells”
Context: No dose given.
“now kpv is a tiny tripeptide fraction of alpha mesite stimulating hormone. It has more anti-inflammatory effects actually than the whole peptide, but it actually does not stimulate, um, the banocy, so you don't get the darkening of the skin, which is good, plus it's small so it can absorb orally, can cross the blood bra barrier”
Context: Captions: “alpha mesite” is alpha-melanocyte, “banocy” melanocytes, “blood bra barrier” blood-brain barrier. Oral absorption in people has not been shown in trials; the oral data we found are in mice.