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Sexual health & tanning

Melanotan 1

A tanning peptide; approved only as an implant for a rare disease.

StatusApproved as an implant for EPP (EU/US); injectable not approved
How well studied in peopleApproved medicine
Experts quoted2 experts

iNot medical advice. We don’t recommend any dose. Every dose below is a quote from the person named, describing their views or their own use. Afamelanotide (Scenesse) is approved in the EU and US only as a doctor-inserted implant for erythropoietic protoporphyria. Melanotan 1 sold online for injection is an unlicensed research chemical.

What experts say about dosing

2 statements from 2 people. Each one is word for word: we add punctuation only and mark cuts with […]. The chips repeat the exact words used.

Jay CampbellAuthor and podcaster on hormones and peptides; co-founder of a peptide company

Own use: three times a week

Dose
“500 mcg”
How often
“3 times a week”
How taken
“injected subcutaneously”
When
“doses evenly spaced out within the week”

“HOW I USE MELANOTAN 1: 500 mcg injected subcutaneously 3 times a week, with the doses evenly spaced out within the week.”

Read the sourceJay Campbell’s Fully Optimized Peptide Stack For 2022 (jaycampbell.com) · 13 Oct 2022

Context: Own use, from an article listing “the peptides I am using nearly every day”. He says he takes it for a calm state of mind rather than for tanning, and that he no longer uses Melanotan 2.

Ben GreenfieldFitness and longevity author; host of Ben Greenfield Life

Full-body stack

Dose
“500 mcg”
How often
“three times a week”
How taken
“injected subcutaneously”
When
“doses evenly spaced out within the week”

“Melanotan-1: 500 mcg injected subcutaneously three times a week, with the doses evenly spaced out within the week.”

Read the sourceWhat Are Peptides? Find Out the Best Peptide Stacks (bengreenfieldlife.com) · 18 Dec 2023

Context: From a list of stacks he says he recommends. Just before the list he writes that he has discussed his favourite stacks “with Jay Campbell” and does not want to reinvent the wheel; the wording matches Jay Campbell’s 2022 own-use article almost exactly, so this is best read as Greenfield endorsing the same protocol rather than as a separate one.

What experts say about safety

0 statements from 0 people about risks and how strong the evidence is.

No expert safety statements are listed yet.

Go deeper

What the research used

Context, not a dosing guide. The trials below tested a 16 mg implant every 60 days in people with a rare skin disease, not injections in healthy people. They do not tell you a dose for tanning or other uses.

Human trials

StudyStudied inWhat the study usedWhat it found
Langendonk et al., 2015, N Engl J MedPubMed 26132941168 people with erythropoietic protoporphyria (EU and US trials)16 mg afamelanotide implant under the skin every 60 days vs placeboMore pain-free time in sunlight and better quality of life; side effects mostly mild
What we don’t know yet
  • The approved product is an implant used under specialist care.
  • No trials of self-injected Melanotan 1 in healthy people.
  • Melanotan 1 is different from Melanotan 2, which acts on more receptors and has more side effects.
  • Products sold online as research peptides are unregulated, so identity, purity and dose accuracy vary.
Common questions

Is Melanotan 1 the same as Melanotan 2?

No. Melanotan 1 (afamelanotide) acts mainly on the pigment receptor; Melanotan 2 also acts on receptors involved in appetite and arousal.

Why do the two quotes look the same?

Ben Greenfield’s 2023 list repeats, almost word for word, the protocol Jay Campbell published in 2022 as his own use. We show both and say so on the card.

Why does the protocol section only contain quotes?

We do not write our own dose ranges. The protocol cards show, word for word, what named people have publicly said, with their caveats and a link to the source.

About this page

Word-for-word statements about how Melanotan 1 (MT-1) is used, each with a link to the source. Its approved form, afamelanotide, is an implant for a rare light-sensitivity disease; the injectable research peptide is a different product. The research is listed separately as context.

Also known as
MT-1; afamelanotide; [Nle4, D-Phe7]-α-MSH; brand name Scenesse (implant)
Type
Synthetic α-MSH analogue (melanocortin-1 receptor agonist)
Last updated
11 Oct 2026

Last reviewed 11 Oct 2026 · Compiled by the Peptide Dosing editorial team · How we check quotes