Weight & metabolismSemaglutide
The weight-loss and diabetes medicine sold as Ozempic and Wegovy.
4 experts
Approved medicine
Weight & metabolismTirzepatideThe weight-loss and diabetes medicine sold as Mounjaro and Zepbound.
3 experts
Approved medicine
Weight & metabolismRetatrutideAn experimental weight-loss drug still in clinical trials.
7 experts
Tested in clinical trials
Weight & metabolismCagrilintideAn experimental appetite drug, tested together with semaglutide.
1 expert
Tested in clinical trials
Weight & metabolismAOD-9604A piece of the growth-hormone molecule, discussed for fat loss.
5 experts
Tested in clinical trials
Weight & metabolism5-Amino-1MQAn injectable quinolinium compound discussed for fat loss.
3 experts
Animal & lab only
How well studied in people
- SemaglutideApproved medicine
- TirzepatideApproved medicine
- RetatrutideTested in clinical trials
- CagrilintideTested in clinical trials
- AOD-9604Tested in clinical trials
- 5-Amino-1MQAnimal & lab only
About this category
Incretin medicines such as semaglutide and tirzepatide are approved for type 2 diabetes and, in some places, for weight management. Other compounds listed here are researched or discussed for appetite, fat loss or metabolism but are not the same class of approved drug. Comparisons between them are among the most common searches on this topic.