Lee is a US board-certified endocrinologist and a co-founder of the Clinical Peptide Society. He co-authored a small retrospective study of BPC-157 injected into the knee (listed in the BPC-157 research section). Quotes here come from his interview on The Dr. Hyman Show; we only use turns where the transcript names him as the speaker.
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“So generally I tell my patients to use like, uh, 250 micrograms, um, of, uh, thus onha one like once or twice a week, just as, as just, not daily. You can use daily if you're sick, like higher doses […] so I gave her about one, one milligram of thus Alpha One. Next morning she was perfect.”
Watch at 21:55The Peptide That Heals Tendons, Joints & Injuries Faster Than Anything Else (The Dr. Hyman Show, with Dr Edwin Lee) · 26 Jun 2024 · Read the episode page
Context: “thus onha one” and “thus Alpha One” are how the captions render thymosin alpha-1. The second part is about giving his wife a single dose when she was coming down with a cold, around 2016. The drhyman.com transcript labels this turn “Dr. Edwin Lee”.
“I love epith thalon, uh, then generally we do five milligrams, uh, subq daily for like 10 days. If you skip a day or like the weekend, you forget, that's okay, just, just make sure you finish the V […] so like 10 days twice a year. It's kind of a reset for your longevity, um, and I have people like, for me when I was doing it, it's amazing, my sleep.”
Watch at 23:08The Peptide That Heals Tendons, Joints & Injuries Faster Than Anything Else (The Dr. Hyman Show, with Dr Edwin Lee) · 26 Jun 2024 · Read the episode page
Context: Answering Mark Hyman’s question “what else besides T1 and BPC-157?”. He goes on to describe his own sleep improving. “V” is the vial. The cut sentence about vial size is garbled in the captions. The drhyman.com transcript wrongly gives the first line to Hyman; the follow-on about his own use and his wife is labelled “Dr. Edwin Lee”, and Hyman replies “So you said it twice a year”.
“10 milligrams once a week or 5 milligrams twice a week”
How often
“once to two times a week”
How taken
“sub Q”
“I, I, I do it intermittently […] you can do the protocols 10 milligrams once a week or 5 milligrams sub Q twice a week, um, you could go a little further if you have an event, like you're, you're, you're trying to like, yeah, run faster, like you have a marathon coming up or something like that, but in general just, uh, once to two times a week”
Watch at 40:42The Peptide That Heals Tendons, Joints & Injuries Faster Than Anything Else (The Dr. Hyman Show, with Dr Edwin Lee) · 26 Jun 2024 · Read the episode page
Context: Answering Mark Hyman, who asks whether it is something you use every day long term and then “could you use it every day?”. He says he has tried it himself and prefers it as an IV push because injections of it burn. The captions render MOTS-c as “MSI”. Labelled “Dr. Edwin Lee” in the drhyman.com transcript.
“EXPERIMENTAL DOSING FOR OPTIMAL BRAIN FUNCTION • Cerebrolysin comes in a 10 ml ampule, inject 1 ml IM once a week to 2-3 times a week. • The rest of the 9 ml draw up with a needle and syringe with use a filter. Store in a sterile vial (amber vial) for multiuse”
Read the source (at p. 25)Neuro regenerative Peptides, conference slides by Edwin Lee MD (agemed.org, PDF) · upload date not confirmed
Context: His own heading calls this “experimental”. IM means injected into a muscle. From his conference slides for doctors (Age Management Medicine Group); the slides are undated.
Slides for doctors: the study doses and his “optional dosing”
Dose
“30 ml IV infusion, or 1 ml (215.2 mg) IM”
How often
“IV 2-3 times a week; IM 3-5 times a week”
How taken
“IV infusion or IM”
“• Dosing used in studies were 10- 30 ml/ day IV 5 days a week. • Concentration is 215.2 mg/ml • Comes in 10 ml ampules • Optional dosing • Infuse 30 ml (6456 mg) in 250 cc of normal saline over 1 hour 2-3 times a week. Recommend using a filter • 1 ml (215.2 mg) IM shot 3-5 times a week”
Read the source (at p. 24)Neuro regenerative Peptides, conference slides by Edwin Lee MD (agemed.org, PDF) · upload date not confirmed
Context: The first line summarises the hospital studies (given by drip into a vein, IV); “optional dosing” is his own suggestion. An IV infusion is given in a clinic. From his conference slides for doctors (Age Management Medicine Group); the slides are undated.
Slides for doctors: one spray in each nostril daily
Dose
“750 mcg per nasal spray in each nostril (total 1500 mcg)”
How often
“once a day”
How taken
“intranasal”
“• Suggested dosing • 750 mcg per nasal spray in each nostril once a day. (total dose of 1500 mcg) • The stroke studies used up 18 mg a day”
Read the source (at p. 44)Neuro regenerative Peptides, conference slides by Edwin Lee MD (agemed.org, PDF) · upload date not confirmed
Context: On the same slide he notes that Semax has poor oral delivery and can be given under the skin or into the nose. From his conference slides for doctors (Age Management Medicine Group); the slides are undated.
“75 μg per spray; 1-2 sprays per dose (max 675 μg/day)”
How often
“2- 3 doses per day”
How taken
“nasal spray”
“• Suggested dosing […] • 75 μg of Selank per nasal spray. The recommended dosage is 1-2 sprays per dose with 2- 3 doses per day (a max total of 675 μg/day)”
Read the source (at p. 50)Neuro regenerative Peptides, conference slides by Edwin Lee MD (agemed.org, PDF) · upload date not confirmed
Context: The cut bullets say Selank has poor oral delivery and can be given under the skin or into the nose. From his conference slides for doctors (Age Management Medicine Group); the slides are undated.