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Growth hormone boosters

GHRP-6

An older growth-hormone-releasing peptide known for strong hunger.

StatusNot approved; WADA prohibited
How well studied in peopleSmall human studies
Experts quoted4 experts

iNot medical advice. We don’t recommend any dose. Every dose below is a quote from the person named, describing their views or their own use. GHRP-6 is not an approved medicine anywhere and is on the World Anti-Doping Agency prohibited list. Products sold online are research chemicals.

What experts say about dosing

3 statements from 3 people. Each one is word for word: we add punctuation only and mark cuts with […]. The chips repeat the exact words used.

Ben GreenfieldFitness and longevity author; host of Ben Greenfield Life

Dose range and empty stomach

Dose
“100-150 mcg per injection”
How often
“1-4X per day”
When
“on an empty stomach”

“This is why GHRP-6 should be administered on an empty stomach (no food should be consumed for 15-20 minutes post-injection if maximum GH release is desired. In addition when using GHRP-6 for GH release, the average dosing range is between 100-150 mcg per injection and dosing frequency is between 1-4X per day.”

Read the sourceHow To Use Growth Hormone Stacks For A Better Body (bengreenfieldlife.com) · 7 Nov 2016

Context: From his 2016 growth-hormone stack article. The opening bracket is not closed in the original. He adds that GHRP-6 “should be combined with a GHRH” for maximal GH release.

Vigorous SteveBodybuilding coach and YouTuber (VigorousSteve)

GHRP-6 (GH cheat-sheet)

Dose
“100 microgr to 200 microgram”
How often
“up to three times daily”
How taken
“subcutaneously”

“growth hormone releasing peptide 6 ghrp6 100 microgr to 200 microgram subcutaneously up to three times daily”

Watch at 7:20MAXIMIZE Growth Hormone With Ipamorelin & Tesamorelin (Cheat-Sheet) MK-677, GHRP-6, CJC-1295 & More! · 30 Jan 2024

Context: One line from a spoken cheat-sheet of ghrelin-receptor agonists; just before, he says most people would use a GHRH-receptor agonist “once or twice per day in combination with a” ghrelin-receptor agonist. “microgr” is how the auto-captions render microgram.

Dr Craig KoniverPhysician; founder of Koniver Wellness (Charleston, US, and London)

Same 100 mcg as hexarelin and ipamorelin

Dose
“100 micrograms”

“A 100 micrograms. It's the same as these other, like ipamorelin, GHRP-6, a 100 micrograms.”

Read the sourceDr. Craig Koniver: Peptide & Hormone Therapies for Health, Performance & Longevity (Huberman Lab transcript) · 7 Oct 2024

Context: Answering Andrew Huberman’s question about the hexarelin dose he typically prescribes; he puts GHRP-6 at the same amount. How often is not stated in this answer.

What experts say about safety

2 statements from 2 people about risks and how strong the evidence is.

Ben GreenfieldFitness and longevity author; host of Ben Greenfield Life

Side effects of GHRPs

“When used in excessive quantities or excessive frequencies, or stacked incorrectly with the other compounds you’ll learn about in this article, all GHRP’s also share a few common negative side effects: specifically water retention, excessive sleepiness, tightness or carpel tunnel-like symptoms in the wrist/hand, numbness and tingling in the extremities, and a decrease in insulin sensitivity.”

Read the sourceHow To Use Growth Hormone Stacks For A Better Body (bengreenfieldlife.com) · 7 Nov 2016

Context: In the same article he writes that “compared to GHRP-2, GHRP-6 tends to cause a huge increase in hunger.”

Nicholas TrigiliHuman performance specialist and coach; fitness YouTuber

Tier list: C tier

“GHRP-6 and GHRP-2 are C-tier in 2026. They were staples 10-15 years ago, but they have been superseded. Both cause cortisol and prolactin spikes that are absent with ipamorelin. GHRP-6 triggers significant hunger, which is counterproductive in a fat loss context.”

Read the sourceBest and Worst Peptides to Experiment With in 2026: Complete Tier List (nicholastrigilipress.com article) · 17 Jan 2026

Context: No dose given.

Go deeper

What the research used

Context, not a dosing guide. The human studies of GHRP-6 are short, small studies that measured the growth-hormone response to single doses, given by vein or by mouth and dosed by body weight. They do not establish a dose for repeated use.

Human studies

StudyStudied inWhat the study usedWhat it found
Bowers et al., 1992, J Clin Endocrinol MetabPubMed 17308075 healthy men and 9 children of short statureSingle oral doses of 100 and 300 µg/kgGH peaked 60–75 min after the dose; the higher dose gave the larger rise
Pandya et al., 1998, J Clin Endocrinol MetabPubMed 9543138Healthy volunteersGHRP-6 by vein, with or without GHRHMaximal GH release required the body’s own GHRH
What we don’t know yet
  • Only short single-dose studies in people; no trials of repeated use.
  • Raises cortisol and prolactin as well as GH, and strongly increases hunger (see the expert quotes).
  • Grey-market products are unregulated, so identity, purity and dose accuracy vary.
Common questions

How is GHRP-6 different from ipamorelin?

Both act on the ghrelin receptor. Ben Greenfield and Nicholas Trigili describe GHRP-6 as causing much more hunger, and Nicholas Trigili says it raises cortisol and prolactin, which ipamorelin does not.

Why does the protocol section only contain quotes?

We do not write our own dose ranges. The protocol cards show, word for word, what named people have publicly said, with their caveats and a link to the source.

About this page

Word-for-word statements about how GHRP-6, one of the first growth-hormone-releasing peptides, is used, each with a link to the source. The published research is listed separately as context.

Also known as
Growth hormone releasing peptide-6; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Type
Synthetic hexapeptide; ghrelin-receptor agonist
Last updated
11 Oct 2026

Last reviewed 11 Oct 2026 · Compiled by the Peptide Dosing editorial team · How we check quotes