iNot medical advice. We don’t recommend any dose. Every dose below is a quote from the person named, describing their views or their own use. CJC-1295 is not an approved medicine in the EU, UK or US. It is prohibited by WADA.
7 statements from 5 people. Each one is word for word: we add punctuation only and mark cuts with […]. The chips repeat the exact words used.
“[…] no drug Affinity complex, that's what Dak stands for. We have a dosages ranging between 150 micrograms to 300 micrograms administered subcutaneously up to three times daily”
Context: From his spoken GH cheat-sheet. “Dak” is the auto-caption spelling of DAC (drug affinity complex).
“But if you want less injection frequency I would go with CJC 1295 with the drug Affinity complex, which allows for once per week administrations between 1 milligram to 2 milligram subcutaneous one time weekly”
Context: Directly follows the no-DAC line above.
“So, CJC-1295 typically is only taken twice per week or even once per week because its effects on increasing growth hormone and IGF-1 last several days”
Context: Descriptive: he is explaining the long-acting DAC version, and immediately follows with the safety concern below. He gives no dose.
“For this stack, you’ll want to use CJC without DAC (drug affinity complex), which is the shorter-acting version that more closely mimics your body’s natural growth hormone pulses. Dosing Guidelines: 100mcg 1–3x/day for a 12-week cycle; OR 10mL of 2000mcg/ml solution 1x/day, 5 nights per week. Administration Route: Subcutaneous injection. Timing Tips: Take CJC-1295 before bedtime on an empty stomach.”
Context: Published as “Dosing Guidelines” in his muscle gain/fat-loss stack, not labelled as his own use. Bullet points joined into one line.
“Now you can inject these together always subcutaneously not interuscularly. And the best timing options are typically if you're going to use them both at the same time half that dose in the morning first thing in the morning when you get up half the dose right before bedtime. And the frequency, like I said, five days on, two days off. And the rest strategy, always try to take off two days in a row.”
Context: About CJC-1295 without DAC with ipamorelin. The per-injection figures he gives just before are captioned “1 to 200 micrograms” (CJC-1295) and “2 to 300 micrograms” (ipamorelin); we have held them for a listen. His later video (above) says to take both before bed. He says in his videos that he is not a doctor.
“The dosing for these peptides CJC-1295 sits at about 200 to 400 micrograms combined with ipamorelin about 100 micrograms to 300 micrograms subcutaneous injection taken together right before bed 5 days a week is the best entry point into GH optimization on it entire list.”
Context: From a fat-loss tier list; he does not say whether this is CJC-1295 with or without DAC. Caption spelling of the compound name corrected: “CJC25” → CJC-1295; “iMlan” → ipamorelin. He says in his videos that he is not a doctor.
“Many peptide clinics, including ours, use doses in the ballpark of, say, 100 micrograms of CJC 1295 and upwards of 150 to 250 micrograms of Ipamorelin. This can vary based off your goals and your response, but that's the ballpark most people start. You don't boost up the CJC. You have a saturation level of about 100 micrograms of CJC. But, the Ipamorelin, you can go up to probably 250, 300 before you get to that saturation point if you really want to improve the results. Cycling. A common protocol, 5 days on, 2 days off”
Context: The two are used together. He does not say whether the CJC-1295 is the version with or without DAC. Just before this he says a second daily dose would go first thing in the morning, fasted.
4 statements from 1 person about risks and how strong the evidence is.
“But, keep in mind that CJC-1295 has entered clinical trials. There was a death within one of the clinical trials that was related to cardiovascular dysfunction. It's known to cause some fluid retention and increased fluid volume, which may have been related to that cardiovascular death. We don't know, okay? This is all kind of speculation.”
Context: Wording follows the official hubermanlab.com transcript; YouTube’s captions read “which may be have been related”.
“And to my mind, given that there are decent alternatives in sermorelin or tesamorelin, I don't know why anyone would specifically select CJC-1295 until all these safety issues have been resolved.”
Context: Closing remark of his CJC-1295 segment.
“While I'm not opposed to that approach, you just want to make sure that the dosing, or I should say the relative dosing of each peptide is such that, you know, you're avoiding unnecessary increases in prolactin and cortisol, and that you're not hitting a pathway redundantly.”
Context: Said about people who combine ipamorelin with CJC-1295.
“If you're younger than 30, I don't know why you'd want to augment growth hormone unless you and your doctor decide that there's a clinical need or some other urgent need to do so because you're already making a lot of growth hormone. If you're older than 30 and you're interested in using these compounds, to me it stands to reason that of course you want to make sure that you don't have any tumors or cancers that you could potentially exacerbate. But in addition to that, that you really think about using the minimal effective dose and that you use perhaps even the mildest of these different compounds […]”
Context: Said in his closing summary on growth-hormone secretagogues as a group (sermorelin, tesamorelin, CJC-1295, ipamorelin and others), not about this compound alone.
Context, not a dosing guide. These studies used CJC-1295 with DAC in small groups of healthy adults. “CJC-1295 without DAC” (Mod GRF 1-29) is a different molecule with no comparable published trials. None of these studies establishes a safe or effective dose.
| Study | Studied in | What the study used | What it found |
|---|---|---|---|
| Teichman et al., 2006, J Clin Endocrinol MetabPubMed 16352683 | Healthy adults | Single and repeated weekly or biweekly subcutaneous doses | GH up 2–10-fold for 6 days or more; IGF-1 up 1.5–3-fold; half-life 5.8–8.1 days; no serious adverse reactions |
| Ionescu & Frohman, 2006, J Clin Endocrinol MetabPubMed 17018654 | Healthy men | Single dose of 60 or 90 µg/kg | GH pulsatility preserved; trough GH up 7.5-fold; IGF-1 up 45% |
DAC (drug affinity complex) lets the peptide bind albumin, so it lasts days instead of minutes. “Without DAC” products are usually Mod GRF 1-29, a different, short-acting molecule.
No. Clinical development was discontinued and it is not approved anywhere.
See his quote under Safety & evidence. He stresses that the link to the drug is speculative.
We do not write our own dose ranges. The protocol cards show what named people have publicly said, with a link to the source.
Word-for-word statements about how CJC-1295 (with and without DAC) is used and about its safety record, each with a link to the source. The published research is listed separately as context.
Last reviewed 11 Oct 2026 · Compiled by the Peptide Dosing editorial team · How we check quotes