Sermorelin vs Tesamorelin

“Tesamorelin is a bit more long-lasting than sermorelin and therefore is taken typically about three times per week, not five times per week.”

“By the way, the typical dosages of sermorelin that are um taken are anywhere from 200 to 400 micrograms. Typically, that's done at night before sleep for the reasons that we talked about before. And typically, people will take it anywhere from three times per week or five times per week. There are some disadvantages to taking it continuously 7 days per week for long periods of time. There's some desensitization that can occur. Not much, but some can occur.”

“so somorin is a ghrh analog right so again it mimics what we do in the brain and the dosing for somorin is 500 micrograms twice a day 5 days on two days off”

“Then sermorelin has actually a very broad dosing range anywhere from 200 micrograms. I've used it up to 3,000 micrograms-”

“Sermorelin, you could start with anywhere between 250 to 500 micrograms daily. I've had guys go up to 1 milligram daily. […] You can inject them together subcutaneously. Now timing I always stick with something very similar just like I mentioned earlier with the five days on two days off approach.”

“Tesamorelin dose: 1 mg right before bed yet 90 minutes after your last meal, and 1 mg upon waking yet ideally before exercise (via subcutaneous injection)”

“and tesamorelin 1 milligram to 2 milligram subcutaneous up to three times daily”

“Tesamorelin is a bit more long-lasting than sermorelin and therefore is taken typically about three times per week, not five times per week.”

“Dosing Guidelines: 1mg 1–2x/day for 5 days per week for a 6–8 week cycle; OR 5mL of 1mg/0.6mL solution 1x/day, 6 days per week for a 6–8 week cycle. Administration Route: Subcutaneous injection. Timing Tips: Before bed, take it at least 90 minutes after eating. Upon waking, take tesamorelin ideally before exercise and eating.”

“The two that are different would be tesamorelin, ideal dose 2 milligrams per dose, which is 2,000 micrograms, so quite different.”

“Now, my experiments, don't copy these. I've used tesamorelin up to 2 milligrams a day, four to five to six times a week, never every day with these peptides. And I'm going to use this peptide for 16 to 30 to 40 weeks”

“the FDA-labeled dose is around 1 to 2 mg daily. But, that 2 mg, I've never seen anybody take that off-label. In our clinic, we use different dosing and often a cycling schedule. Timing matters. We have patients take it away from meals, often in the evenings. Food, especially carbohydrates, will blunt the growth hormone release. So, an empty stomach helps maximize the goals. Think 1 mg at the most. 500 micrograms to 1,000 micrograms, 5 days on, 2 days off before bed.”